• br Discussion CRT has become an established adjunctive treat

  2019-06-15

  

  Discussion CRT has become an established adjunctive treatment to optimal pharmacological therapy in patients with advanced CHF, diminished LV function, and intra-ventricular conduction delay [8]. Despite the benefits of CRT including improvements in exercise capacity, functional class, and ventri

• br Methods br Results br Discussion The

  2019-06-15

  

  Methods Results Discussion The results of this study demonstrate that (1) low-dose landiolol (0.5μgkg−1min−1) prevent heart rate elevation after AF ablation; (2) prophylactic administration of low-dose landiolol successfully prevented immediate AF recurrence within 3d after AF ablation with

• br Conclusions and future perspectives

  2019-06-15

  

  Conclusions and future perspectives Conflict of interest Author’s contributions Introduction Sulfotransferase (SULT)-mediated sulfation and steroid sulfatase (STS)-mediated desulfation represent two opposing mechanisms involved in regulating the chemical and functional homeostasis of end

• There is strong agreement that HIV prevention

  2019-06-15

  

  There is strong agreement that HIV prevention should focus on approaches that are evidence based, but there is disagreement about how to obtain such rigorous evidence and whether this should refer only to randomised study designs. Pickles and colleagues\' report provides a concrete example of an eff

• br Tuberculosis remains a global emergency and continues

  2019-06-15

  

  Tuberculosis remains a global emergency and continues to present major public health challenges worldwide. The actual global burden of tuberculosis can only be estimated because no accurate data are available from national country programmes from of high tuberculosis endemic countries. The WHO 201

• br Hospitals in low income and middle income countries

  2019-06-15

  

  Hospitals in low-income and middle-income countries receive surgical patients late, and usually when they are critically ill. Consequently, high perioperative mortality and poor surgical outcomes are the unacceptable results of the provision of surgical health care in these countries. However, the

• En la obra de Cuadra una familia campesina

  2019-06-14

  

  En la obra de Cuadra, una familia campesina confronta trágicamente la guerra civil entre conservadores y liberales. Víctimas pasivas de las élites y no actores políticos, estos campesinos ven cómo los principios familiares tradicionales y del minifundio son desarticulados por la guerra y el abuso de

• br Water the main component of Earth s

  2019-06-14

  

  Water—the main component of Earth\'s ecosystems—concentrates some of the most worrying global concerns that have emerged during the Anthropocene. When it comes to health considered at a planetary level, the challenges related to water can be sorted into five main categories: pollution, access to w

• In Helen Nabwera and colleagues describe how

  2019-06-14

  

  In Helen Nabwera and colleagues describe how child growth in a rural African setting has changed during four decades of public health interventions. The investigators analysed data from an unparalleled resource: longitudinal growth monitoring across three Gambian villages spanning 36 years. The lon

• br Acknowledgments We thank all the ultramarathon runners wh

  2019-06-14

  

  Acknowledgments We thank all the ultramarathon runners who participated in this study and all the doctors, nurses, and emergency medical technicians who provided professional care at the ultramarathon race. We also thank our colleagues at Soochow University, Taipei, Taiwan and the Chinese Taipei

• The miR signature of exosomes isolated from bulk prostate

  2019-06-14

  

  The miR signature of exosomes isolated from bulk prostate cancer mglur antagonist (Fig. 1A, blue cells) and from their cancer stem cell compartment (Fig. 1A, green cells), display high levels of miR-21, miR-30 and miR-218 [23] (Fig. 1A, blue arrow). miR-21 and miR-30 have been identified as key reg

• br Case report A year old man

  2019-06-14

  

  Case report A 63-year-old man with a history of longstanding atrial fibrillation (AF) was admitted to our hospital with anterior acute myocardial infarction (AMI). Emergency cardiac catheterization revealed chronic total occlusion of the distal right coronary artery, total occlusion of the proxim

• Introduction Focused ultrasound FUS sonication in the presen

  2019-06-14

  

  Introduction Focused ultrasound (FUS) sonication in the presence of microbubbles (MB) can disrupt the BBB, increasing its permeability. This type of disruption is transient and reversible, and does not damage neural cells. The oscillation and destruction of microbubbles as well as microstreaming an

• We propose that the same geospatial statistical techniques c

  2019-06-14

  

  We propose that the same geospatial statistical techniques can be applied to HIV. We used these techniques to estimate the number of HIV-infected individuals in Maseru (a health-care district in Lesotho) and establish their geographical location. The district of Maseru is a relatively large area, ab

• In Telek Ayove and colleagues report

  2019-06-14

  

  In , Telek Ayove and colleagues report a comparison of the Dual Path Platform (DPP) Syphilis Screen and Confirm test (Chembio Diagnostic Systems, Medford, NY, USA) with non-treponemal (RPR) and treponemal (TPHA) serological tests for diagnosis of yaws in two remote communities in Papua New Guinea wi

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