Archives
- 2025-11
 - 2025-10
 - 2025-09
 - 2025-03
 - 2025-02
 - 2025-01
 - 2024-12
 - 2024-11
 - 2024-10
 - 2024-09
 - 2024-08
 - 2024-07
 - 2024-06
 - 2024-05
 - 2024-04
 - 2024-03
 - 2024-02
 - 2024-01
 - 2023-12
 - 2023-11
 - 2023-10
 - 2023-09
 - 2023-08
 - 2023-07
 - 2023-06
 - 2023-05
 - 2023-04
 - 2023-03
 - 2023-02
 - 2023-01
 - 2022-12
 - 2022-11
 - 2022-10
 - 2022-09
 - 2022-08
 - 2022-07
 - 2022-06
 - 2022-05
 - 2022-04
 - 2022-03
 - 2022-02
 - 2022-01
 - 2021-12
 - 2021-11
 - 2021-10
 - 2021-09
 - 2021-08
 - 2021-07
 - 2021-06
 - 2021-05
 - 2021-04
 - 2021-03
 - 2021-02
 - 2021-01
 - 2020-12
 - 2020-11
 - 2020-10
 - 2020-09
 - 2020-08
 - 2020-07
 - 2020-06
 - 2020-05
 - 2020-04
 - 2020-03
 - 2020-02
 - 2020-01
 - 2019-12
 - 2019-11
 - 2019-10
 - 2019-09
 - 2019-08
 - 2019-07
 - 2019-06
 - 2019-05
 - 2019-04
 - 2018-11
 - 2018-10
 - 2018-07
 
- 
                
          
Similar to the importance of
2023-10-19

Similar to the importance of MeJA in postharvest A. bisporus quality maintenance at 10°C storage (Meng et al., 2012a), MeJA was also observed to play a pivotal role in this event at 4°C storage. Cap opening is an important mushroom quality indicator (Braaksma et al., 1999). During postharvest storag
 - 
                
          
Based on its kinetic parameters and quaternary structure
2023-10-19

Based on its kinetic parameters and quaternary structure, R. pycnus arginase is a typical ureotelic L-arginase [2]. The Km value of the enzyme was lower than other arginases from other organisms (Table 2), including S. cerevisiae (15.7mM), B. anthracis (10mM), B. caldovelox (3.4mM), human liver (2.3
 - 
                
          
In our approach using BRET and FRET there
2023-10-19

In our approach using BRET and FRET, there is a substantial increase in BRET and FRET signals between Giα2 or Giα3-YFP and CFP- Gγ2/Rluc-Gγ2 upon apelin-13 activation, indicating that Gαi2, Gαi3 and N-terminus of Gβ1γ2 subunits become closer without subunit dissociation. In contrast, both the FRET a
 - 
                
          
br Materials and methods br Results br Discussion Recently
2023-10-19

Materials and methods Results Discussion Recently, we showed that stimulation of TRPM3 and TRPC6 channels triggers a signaling cascade leading to the activation of AP-1 [11], [12], [13], [15]. The objective of this study was to investigate whether stimulation of TRPV1 channels leads to an a
 - 
                
          
Fish aminopeptidases from Alaska Pollack roe and tuna pylori
2023-10-18

Fish aminopeptidases from Alaska Pollack roe and tuna pyloric caeca have been reported on [12,13]. More recently, we described the purification of a leucine aminopeptidase from the skeletal muscle of the common carp [14], red sea bream [15] and a lysine aminopeptidases from Japanese flounder [16]. T
 - 
                
          
Two cell surface trans membrane receptors have been identifi
2023-10-18

Two cell-surface trans-membrane receptors have been identified for adiponectin, AdipoR1 and AdipoR2 [21], and adiponectin action is known to signal through these receptors and the docking protein APPL1 [22]. In muscle and liver cells, signal transduction involves the phosphorylation and activation o
 - 
                
          
Application of the broad acting HTR antagonist methiothepin
2023-10-18

Application of the broad-acting 5-HTR antagonist methiothepin (Bard et al., 1996, Hoyer et al., 1994, Peroutka, 1990) converted the TBS-induced response of both thalamocortical and intracortical A1 synapses from LTP to LTD, an effect that was mimicked by the selective 5-HT2R antagonist ketanserin (L
 - 
                
          
Diabetes or inflammation is associated with up regulation
2023-10-18

Diabetes or inflammation is associated with up-regulation of A2AAR (Pang et al., 2010). High levels of A2AARs are found in macrophages and microglial cells that are poised, on activation, to abrogate the immune response (Trincavelli et al., 2008). In addition, hyperglycemia is associated with increa
 - 
                
          
br Conclusion br Conflicts of Interest Disclosures br Acknow
2023-10-18

Conclusion Conflicts of Interest/Disclosures Acknowledgement This study was funded by the Ministry of Science of the Republic of Serbia (grant #175083). Introduction Myasthenia gravis (MG) is an antibody-mediated, neuromuscular transmission disorder, where the targets are postsynaptic p
 - 
                
          
It has been suggested that
2023-10-18

It has been suggested that the suppression of 5-LOX could promote apoptotic signaling pathways in cancers [6]. However, the role of 5-LOX in modulating apoptotic factors and neutrophil activation during ANP has not yet been evaluated. In this study, we aimed to evaluate the expression of 5-LOX in pa
 - 
                
          
The synthesis and secretion of adrenal androgens is apparent
2023-10-18

The synthesis and secretion of adrenal androgens is apparently unique to humans and nonhuman primates, and requires the expression of key mediators such as CYP17 [26]. Endocrine control of CYP17 expression in rhesus monkeys is comparable to that in humans [27]. An analysis of baboon cDNA for CYP17 s
 - 
                
          
Cy5.5 NHS ester Our sample is representative of
2023-10-18

Our sample is representative of mRCC treated with sunitinib. However, the results from CCC setting have limited inference due to small exploratory sample (n = 51). Additionally, the significance of survival differences in CCC according to AXL staining is tangential. Unfortunately, we were unable to
 - 
                
          
br Concluding remarks Autophagy ensures cell
2023-10-18

Concluding remarks Autophagy ensures cell homeostasis and survival through the continuous degradation/recycling of intracellular components. It can also represent a conserved, cell-intrinsic, defense mechanism against invading pathogens, including viruses. The autophagy process can be activated r
 - 
                
          
Loss of virulence in ACL mutants may be
2023-10-18

Loss of virulence in ACL mutants may be caused by defect in vegetative growth and conidial germination, and reduced trichothecene production. However, supplement of potassium acetate restored the defects in germination rate and vegetative growth, but not virulence in wheat heads (Table 2, Fig. 2B),
 - 
                
          
Neuropathic animals display increased sensitivity to the
2023-10-18

Neuropathic animals display increased sensitivity to the anti-nociceptive effect of baclofen and whilst the number and affinity of GABAB Amrubicin synthesis in the dorsal horn are not altered (Smith et al., 1994; Zemoura et al., 2016), GABAB receptors subunits (B1 and B2) are both down-regulated in
 
16559 records 274/1104 page Previous Next First page 上5页 271272273274275 下5页 Last page