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Natural progestogens play an important role in the stimulati
2020-08-17
Natural progestogens play an important role in the stimulation of oocyte growth and maturation as well as in spermatogenesis and sperm maturation, and they act as sex pheromones in teleost fish (Kime, 1990, Kobayashi et al., 2002, Nagahama and Yamashita, 2008, Scott et al., 2010). A complex series o
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Tigecycline br Discussion Estradiol is known as one
2020-08-17
Discussion Estradiol is known as one of the stress signaling molecule [3,4,14]. Here, we showed that PH induced estradiol production before hepatocyte proliferation (Fig. 1). Conversely, the ovariectomized and orchitectomized mice produced less estradiol after PH, and had delayed liver regenerati
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Rice approximately covers of land area of the earth
2020-08-17
Rice approximately covers 1% of land area of the earth and it is one of the main sources of food for billions of people [4]. One of the main agriculture industry residues is rice husk, which contains high amount of amorphous silica up to 85–95%. Rice husk ash (RHA) is a solid residue of rice husk co
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price scd receptor br Results br Discussion The advent of TK
2020-08-17
Results Discussion The advent of TKI treatment has greatly improved CML therapy. Because CML LSCs are less sensitive to TKIs, CML is usually controlled rather than cured, highlighting an unmet clinical need. Developed from our previous finding that CML LSCs are more dependent on Tcf1 and Lef1
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br Non cyclic nucleotide EPAC regulators
2020-08-17
Non-cyclic nucleotide EPAC regulators Despite the success of 007 as a tool molecule, few studies to date have led to the identification of further EPAC-selective agonists. The most studied and controversial group of small-molecule EPAC regulators are the sulfonylurea (SU) family. SUs (Table 1) su
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br Materials and methods br Results and discussion
2020-08-14
Materials and methods Results and discussion Conclusions In this study, we have investigated the possibility that hierarchical phosphorylation by CK2 may play a role in cellular signal transduction. Hierarchical phosphorylation by CK2 requires multiple consensus determinants with specific s
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br Conflict of interest br Acknowledgments This
2020-08-14
Conflict of interest Acknowledgments This work was supported in part by grants from the , Spain (INCITE08PXIB203092PR). VGM was supported by a FPU pre-doctoral scholarship from the , Spain. MLR was supported in part by a crowdfunding campaign (PRECIPITA), coordinated by the Spanish Foundation
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br Materials and methods br Results br Discussion The nitric
2020-08-14
Materials and methods Results Discussion The nitric oxide generating enzymes of the NOS family comprise three isoforms: nNOS, iNOS and eNOS [31]. Expression of eNOS is mainly found in endothelial mu receptor antagonist where it physically promotes vasodilation [32]. Conversely, evidence al
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The occurrence of three Ag
2020-08-14
The occurrence of three Ag-NORs per metaphase and/or a maximum of three nucleoli per nucleus in most of the varieties may be explained by chromosomal rearrangements or unequal crossing-over events that induce the deletion of the fourth active rDNA loci. Also, the chromosome pair that showed less int
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methysergide The present work shows that normal climatic
2020-08-14
The present work shows that normal climatic conditions are not critical for the long time survival of DNA in untreated blood stains. This information may be useful for laboratories who wish to store reference blood samples in a simple way, while saving the costs of commercial substrates that are tre
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ap15 The presence of H PPases in parasitic protists raises t
2020-08-14
The presence of H+-PPases in parasitic protists raises the question of the physiological role of these proteins. So far, they had been extensively characterized mainly in higher plants, and some prokaryotes [1], [2], [3], [4], [5], [6], [7], [16], [20]. A common feature to all these organisms is tha
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9-Phenanthrol synthesis Recent studies have shown arsenic co
2020-08-14
Recent studies have shown arsenic could cause autophagic cell death in malignant cells, including leukemia and malignant glioma 9-Phenanthrol synthesis [16], [17]. However, at present, little is known about the consequences of arsenic-treated urothelial cells in autophagy and expression of its relat
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Testosterone is inactivated through hydroxylation and conjug
2020-08-14
Testosterone is inactivated through hydroxylation and conjugation pathways [3], [4]. 6β-Hydroxylation is the main pathway among testosterone hydroxylation processes in the liver microsome. Testosterone 6β-hydroxylation is mainly catalyzed by cytochrome P450 3A (CYP3A) [5], [6], which is expressed in
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So what can we glean from this
2020-08-14
So what can we glean from this illuminative foray into how Chk1 and MK2 participate in checkpoint control? First and foremost, this work reveals that 6656 deficient in the tumor suppressor p53 contain two spatially distinct G2/M phase checkpoint control kinase networks. This provides compelling evi
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In general we observed that the
2020-08-13
In general, we observed that the enolase gene with highest mRNA levels was TVAG_043500, under all three iron concentration conditions. mRNA levels for this gene are very similar in normal and iron rich cultures (73.9 and 78.1 fold change, respectively), and higher in iron depleted cultures (118.3 fo
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