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br Discussion Nowadays the expected long term survival of th
2018-10-30
Discussion Nowadays, the expected long-term survival of the vast majority of patients with CAD is excellent, with few recurrent cardiovascular events (Bauters et al., 2014a). During this prolonged period of outpatient care, diagnostic and therapeutic decisions by the referring cardiologist are ma
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Andexanet alpha is a modified recombinant FXa
2018-10-30
Andexanet alpha is a modified recombinant FXa lacking enzymatic activity which is currently in an earlier stage of development for neutralisation of direct and indirect FXa inhibitors. A phase 3 study to evaluate the effect of andexanet in bleeding patients receiving FXa-inhibitors started in 2015.
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These results do not prove causal relationships between thes
2018-10-30
These results do not prove causal relationships between these genetic variations and phenotypes, but set the stage for replication and mechanistic research to inform precision medicine. Despite the limitation of this preliminary study (notably a small sample size), significant differences were found
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We then went on to see if these proteins
2018-10-29
We then went on to see if these proteins bound non-specifically to an Tozadenant of affinity resins; FLAG, TALON, Calmodulin and IgG and identified hundreds of non-specific interactors for each resin. We compared these lists to identify which proteins bind to multiple resins non-specifically. We ref
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Efforts to reduce life cycle CO emissions
2018-10-29
Efforts to reduce life STA-4783 Supplier CO2 emissions of fuel-efficient cookstoves must focus on reductions in use-phase emissions even if those reductions come at the cost of dramatically increased emissions in other life cycle phases. Take the example of an exceptionally energy-intensive materia
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br Neurodevelopment and social sensitivity during
2018-10-29
Neurodevelopment and social sensitivity during adolescence Adolescence is marked by complex biological and psychological transformations that underlie a wide range of behaviors (Nelson et al., 2005, 2016; Spear 2011). Specifically, adolescent neurodevelopment is characterized by a rapid maturatio
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Motivations for investigating how sleep affects the
2018-10-29
Motivations for investigating how sleep affects the large-scale default mode network (DMN) include: (1) reduced DMN connectivity has been linked to increased impulsivity in children (Inuggi et al., 2014); (2) the DMN undergoes considerable development during adolescence (Fair et al., 2008; Sherman e
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br Flash X ray cinematography set up A schematic of
2018-10-29
Flash X-ray cinematography set-up A schematic of the measurement set-up for flash X-ray cinematography is shown in Fig. 1. Instead of several separate X-ray tubes one multi-anode 450 kV tube is utilized. In the multi-anode tube eight anodes are arranged on a circle of ≈12 cm diameter. This config
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En diciembre de en el ltimo
2018-10-29
En diciembre de 2011, en el último desayuno que le ofreció la Secretaría de Marina al presidente, este justificó su ofensiva bélica comparando a la nación con una casa llena de cucarachas que había que sanear. Las cucarachas eran obviamente los criminales a los cuales había que exterminar; sin embar
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Pene Pero en qu momento te he tratado como
2018-10-29
Pene: ¿Pero en qué momento te he purchase s ibuprofen tratado como inferior? Clítoris: ¿En qué momento de estos últimos cinco mil años? Pene: ¡Pará! Yo no he violado a nadie. Clítoris: Ese es muy buen argumento... para desentenderse del problema, ahora me vas a decir que a los violadores los edu
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br Para cerrar escapar del
2018-10-29
Para cerrar: ¿escapar del género? Preguntarse si el género es un significante vacío permite considerar la importancia de pensar después el espacio semántico construido por dicho término como el lugar potencial de un desacuerdo —dado que los múltiples significados posibles están en debate constant
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Recently as reported by Xu
2018-10-29
Recently, as reported by Xu G et al., sorafenib in combination with low-dose homoharringtonine as a salvage therapy was successfully administrated and obtained CR in primary refractory FLT3-ITD mutant AML. In conclusion, regimen including HHT has been used as an alternative valid front line chemothe
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br Results and analysis br Discussion Comparisons of
2018-10-29
Results and analysis Discussion Comparisons of these results to similar findings among common commercial building projects arguably show that the application of LEED credits truly are weighed differently for hospitality projects. The nine credits found most popular amongst hospitality projects
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br Livable cities in popular media
2018-10-29
Livable cities in popular media and global ranking The term “livable cities” appeared in the popular literature during the 1980s in connection with the growing environmental concerns and the increasing mdm2 p53 among world cities to attract foreign investments and boost their economies. The major
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Only month after the last surgery the patient experienced
2018-10-29
Only 1 month after the last surgery, the patient experienced diplopia with blurred vision, which was accompanied by dizziness, headache, and poor appetite. MRI of the ddr1 showed some leptomeningeal enhancement around the brain stem and suspicion of seeding (Fig. 3A and B). Spinal MRI showed that l
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