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These findings must be interpreted with
2018-10-23
These findings must be interpreted with limitations in mind. The study was a parallel group, longitudinal design typical for assessing treatment effects. However, the control group were healthy adolescents rather than patients randomized to placebo, due to ethical concerns of withholding treatment a
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Though protective against the target diseases DTP may increa
2018-10-23
Though protective against the target diseases, DTP may increase susceptibility to unrelated infections (Aaby et al., 2003b, 2004a, 2012) (Appendix A). The SAGE review noticed that the majority of studies found a detrimental effect of DTP (Higgins et al., 2014). However, SAGE considered the evidence
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The established TDF resistance mutations K
2018-10-23
The established TDF-resistance mutations K65R and K70E have been shown to attenuate virus Epigallocatechin in vitro and in animal models (Miller et al., 2002; Van Rompay et al., 2007; White et al., 2002; Sluis-Cremer et al., 2007). To determine whether these and other TDF-selected TRAMs are associat
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As one of KLF family members KLF was discovered as
2018-10-23
As one of KLF family members, KLF15 was discovered as kidney-enriched KLF, so called as KKLF (). Emerging evidence demonstrates the importance of KLF15 in various physiological and pathophysiological aspects. The physiological functions include the important role in regulating the expression of gen
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Mechanistically the age promoting effects of senescence are
2018-10-23
Mechanistically, the age-promoting effects of senescence are associated with the restriction of regenerative capacity of stem and progenitor dopamine-2 receptor antagonist (Choudhury et al., 2007; Jurk et al., 2014) as well as the secretion of bioactive molecules (the so-called SASP (Coppe et al.,
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The list of all compounds tested by
2018-10-23
The list of all compounds tested by the ITP and in progress is on the ITP website at . To date, six compounds have shown significant extension of lifespan: The positive findings illustrate some important aspects for aging interventions research. The effective interventions appear to include several
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br Acknowledgment Author would like to acknowledge the
2018-10-23
Acknowledgment Author would like to acknowledge the BK 21, Government of Korea (Republic of) for their funding to pursue this research program. Specifications table Value of the data Data, materials and methods Three types of data are presented in this data article and are available in
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The study contributes to define the strategies to reach
2018-10-23
The study contributes to define the strategies to reach high performance order ARQ 621 buildings for Mediterranean climate according with the national requirements. The reduction of CO2 gas emissions, primary energy consumptions and costs have been obtained for several solutions compared to the ref
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Taking in account the fact that krokodil contains
2018-10-23
Taking in account the fact that “krokodil” contains a mixture of morphinans, several mobile phases described in the literature for thin-layer chromatography (TLC) analysis of morphinans were tested [9,10]. For the TLC analysis a mixture of hexane/ethyl acetate/diethylamine was selected as mobile pha
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The explosive was ignited at
2018-10-22
The explosive was ignited at one end of the cylinder at time zero. The density of the explosive was 1.87 g/cm3, and the detonation velocity was 8820 m/s. The AUTODYN “burn on time” model was used for the explosive. The total length of the cylinder with explosive is 10.2 cm. The length of the steel r
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In this context the present investigation describes the
2018-10-22
In this context, the present investigation describes the superiority of DP-GMAW process in welding of AISI: 310S austenitic stainless steel in comparison to the conventional P-GMAW process. The grade AISI: 310S austenitic stainless steel (ASS) is designed for high temperature service due to excellen
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br The experimental set up
2018-10-22
The experimental set up and geometrical data Fig. 1 shows the set up. A brass tube with constant outside diameter and variable inside diameter is used to control the radial expansion velocity of the steel rings. The steel rings were manufactured from projectile bodies of in-service rounds. The te
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The Crystal Palace was probably the first
2018-10-22
The Crystal Palace was probably the first exhibition hall of functionalism that utilized the technological advancement of catalase inhibitor iron and glass for its building materials and light structural frames for its construction. Banham (1974) praised Paxton\'s Crystal Palace for its functional d
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Since the s there have been continuous empirical
2018-10-22
Since the 1970s there have been continuous empirical studies in western countries indicating that adenosine receptor natural environments have therapeutic effects. For instance, Olds (1985) examines the therapeutic effects of nature by interviewing focus groups in a coherent workshop for several ye
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br Enigma cipher machine With these working principles the N
2018-10-22
Enigma cipher machine With these working principles, the NTM is essentially isomorphous with the Enigma machine (Scherbius, 1928; Fischer, 2012) which was used to encipher and to decipher communications in Nazi Germany before and during World War II (this relationship between NTM and Enigma machi
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